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Conclusion: oxandrolone administration is effective in promoting dose-dependent gains in body weight and bcm in hiv-infected men with weight loss. ", keywords = "anabolic steroid, anabolic therapy, atherosclerosis, body composition, cachexia, fat toxicity, lean body mass, lipoproteins, liver function, wasting syndrome",. Objective: to evaluate oxandrolone, an oral anabolic steroid with potent anabolic activity and minimal androgenic effects, for the treatment of aids‐associated myopathy and wasting. Yet, in hiv-affected communities where aggressive prophylaxis for ois like pcp, mac, or fungus are common, wasting is a leading cause of death to people with aids and its becoming clear that many of these deaths are preventable. One effective treatment for hiv-related wasting, oxandrolone, has been available by prescription for over 30 years. Anavar is a brand name behind the steroid with the active substance oxandrolone. A poisonless anabolic agent refers to moderate steroids. It is good for both men and women. Oxandrolone was developed for the treatment of: anemia; turner syndrome; hiv infections; the steroid was also used to restore skin after a burn and to strengthen bones. Oxandrolone, at a dose of either 5 mg/day or 15 mg/day, in contrast to placebo, had a positive impact on the weight and well-being of hiv-seropositive patients suffering from wasting and weakness. Measurable improvement in muscle strength was not noted at the doses employed in this study. Oxandrolone, an anabolic steroid, is used in promoting weight gain and, most important lean body mass (lbm), in patients with hiv-1 disease. The effects of oxandrolone on the body composition in patients with hiv-associated weight loss [abstract]. 5th conference on retroviruses and opportunistic infections; 1998 feb 1–15; chicago 44. Pharo a, salvato p, vergel n, et al. Oxandrolone: anabolic steroid use in hiv positive women [abstract]. "the combination of resistance exercise with a moderately supraphysiologic androgen regimen that included oxandrolone resulted in significantly greater increases in lean tissue and muscle strength than resistance exercise with physiologic testosterone replacement alone in eugonadal hiv-infected men with prior weight loss", the researchers conclude. Oxandrolone belongs to a class of drugs known as anabolic steroids, similar to testosterone. This agent may be used for testosterone replacement therapy in hypogonadal men, in hiv-wasting syndrome, and in other conditions in order to increase nitrogen retention and fat-free muscle mass. Oxandrolone is an orally administered testosterone derivative with a favorable anabolic:androgen ratio and safety profile that has been demonstrated to promote weight and lean tissue gains with a minimization of adverse side effects in hiv-infected individuals. This is a brief review of human immunodeficiency virus (hiv)-associated wasting with expanded discussion of one treatment agent, oxandrolone. Hiv-associated wasting is the involuntary loss of more than 10% of baseline body weight in the presence of chronic diarrhea, weakness, or fever lasting longer than 30 days
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